Pharmacogenomics

SLCO1B1Statins and muscle adverse effects

Transporter function affects exposure to some statins and risk of muscle symptoms.

RELATIONSHIP VALIDITYCPIC clinical guideline
ACTIONABILITYContextual: drug- and dose-specific
SOURCE CHECKLinks and claim boundaries are editorially checked; external expert review is stated only with named disclosure
01

What a test can show

Pharmacogenetic genotype translated into a functional phenotype.

02

Practical meaning

A result may help a clinician individualise statin choice or dose.

03

Where knowledge ends

It does not explain all muscle symptoms or replace assessment of drug interactions.

SOURCES AND VERSION

Verifiable, not ‘trust us’.

Updated: 14 August 2026. Any clinical interpretation requires the exact variant, testing method, family information and medical context.