What a test can show
Genotyping clinically relevant variants with correct phenotype assignment.
Pharmacogenomics
NUDT15Thiopurines
Reduced NUDT15 function is associated with thiopurine intolerance and is particularly relevant in several populations.
RELATIONSHIP VALIDITYCPIC clinical guideline
ACTIONABILITYHigh in thiopurine therapy
SOURCE CHECKLinks and claim boundaries are editorially checked; external expert review is stated only with named disclosure
Practical meaning
Population coverage is part of test quality.
Where knowledge ends
A limited panel can miss rare functional variants.
SOURCES AND VERSION
Verifiable, not ‘trust us’.
Updated: 14 August 2026. Any clinical interpretation requires the exact variant, testing method, family information and medical context.