What a test can show
Validated typing of the specific HLA allele.
Pharmacogenomics
HLA-BHLA-B*57:01 and abacavir
HLA-B*57:01 is associated with high risk of abacavir hypersensitivity.
RELATIONSHIP VALIDITYCPIC clinical guideline
ACTIONABILITYHigh before abacavir use
SOURCE CHECKLinks and claim boundaries are editorially checked; external expert review is stated only with named disclosure
Practical meaning
This is a test for a specific drug–allele pair, not a blanket statement about the whole gene.
Where knowledge ends
A negative result does not rule out every possible drug reaction.
SOURCES AND VERSION
Verifiable, not ‘trust us’.
Updated: 14 August 2026. Any clinical interpretation requires the exact variant, testing method, family information and medical context.