What a test can show
Sequencing plus deletion/duplication analysis; mosaicism may require a tailored strategy.
Monogenic conditions
APCAPC-associated polyposis
Pathogenic variants can cause familial adenomatous polyposis and related phenotypes.
RELATIONSHIP VALIDITYHigh: established causality
ACTIONABILITYHigh after clinical confirmation
SOURCE CHECKLinks and claim boundaries are editorially checked; external expert review is stated only with named disclosure
Practical meaning
Confirmation may change surveillance and family testing.
Where knowledge ends
A normal consumer SNP test does not rule out the syndrome.
SOURCES AND VERSION
Verifiable, not ‘trust us’.
Updated: 14 August 2026. Any clinical interpretation requires the exact variant, testing method, family information and medical context.